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We have tested two NAC derivatives in our cell-based system, both of which appear to have improved pharmacokinetic profiles 28,29,34,35 and they have shown even stronger effects than NAC, suggesting they may be therapeutic options
When intracellular GSH levels were depleted activation of caspase 3 was less, being 30 and 40% for AQ-QI and DEAQ-QI, respectively
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World J Gastroenterol 19(7):10111019
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